At 983 square miles, the watershed is the largest of the four in the region. It is home to Bledsoe Creek State Park, the Taylor Hollow State Natural Area, and several state wildlife management areas including the 6,000 acre Old Hickory Wildlife Management Area.
Sections of Goose Creek and Bledsoe Creek are listed on the Nationwide Rivers Inventory – a federal listing of streams with outstanding scenic, recreational, or cultural attributes. A number of endangered species are found in the watershed, including 10 species of freshwater mussels and the Spring Creek bladderpod, a flower that only blooms in the floodplains of three Old Hickory watershed creeks.